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Knowles Lab

Biophysics & Biophysical Chemistry


2020 - current: PhD in Physics, University of Cambridge, UK

2019-2020: MRes in Nanotechology and Nanoscience, University of Cambridge, UK

2015 - 2019: B.S. in Material Science and Engineering, Clemson University, USA


Sarah's work focuses on developing and optimizing nanopore sensors and microfluidic devices for Multiplexed Analysis of DNA in Clinically Relevant Samples using CRISPR/Cas mechanisms. For this project, she is supervised by both Prof. Tuomas Knowles in Chemistry and Prof. Ulrich Keyser in Physics of Medicine, as well as is partnered with Oxford Nanopore Technologies Ltd.


Key publications: 
Morzy, D, Joshi H, Sandler, S.E. Aksimentiev, A and Keyser, U.F. " Membrane Activity of a DNA-Based Ion Channel Depends on the Stability of Its Double-Stranded Structure" Nano Lett. 2021 (Accepted)
Sandler, S.E, Fellows, B., Mefford, O.T. “Best practices on the analysis of magnetic nanoparticles for biomedical applications”, Anal. Chem. 2019
Fellows, B., Sandler, S.E,, Livingston, J., Fuller, K., Nwandu, L., Bigner, J,. Timmins, S., Lantz, K., Stefik, M. Mefford, O.T “Extended LaMer Synthesis of Cobalt Doped Ferrite” IEEE Magnetic Letters, 2017.